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Herpes simplex virus laryngitis

the two infectious and inflammatory conditions can come in laryngitis, which is divided into acute and chronic forms. more [i]or[/i] less conditions are more frequent in adults, while others are more belonging to all in children. Laryngitis ("croup," epiglottitis, and laryngotracheobronchitis) has many causes, including viral, bacterial, mycotic, or mycobacterial infections, trauma, neoplasms, vascular compromise during surgery iatrogenic injury from feeding tubes or tracheostomy tubes, foreign-body impaction, and radiation therapy. A number of etiologies may be not absent synchronously, such that an infection may unravel in association with radiation therapy, for example. Therefore, multiple etiologies may ne to be addressed.

The findings upon histologic examination may be nonspecific, with edema and an inflammatory infiltrate identified (figure, A). There may be vocal pen compromise and ulceration. Close correlation with the clinical setting--in addition to serology cytologic preparations, microbiologic tillages or tests, precipitant, and other clinical studies (thyroid function ordeals skin tests, etc.)--is imperative to obtain a out and out view of the disease proces Within the necrotic exudate, it is possible to identify specific herpes simplex virus inclusions. Multinucleation and ground-glass-appearing nuclear chromatin distribution are characteristic of a herpes virus infection (figure, B)

[FIGURE OMITTED]



Supportive and specific antiviral therapies can be instituted depending upon the severity of the disease and the patient's immunologic status.

prompted reading

Yeh V Hopp ML Goldstein N Meyer RD Herpes simplex chronic laryngitis and vocal cord lesions in a patient with acquired immunodeficiency syndrome Ann Otol Rhinol Laryngol 1994;103:726-31

Lester DR Thompson MD FASCP

From the Department of Pathology, Woodland Hills Medical Center Southern California Permanente Medical clump Woodland Hills, Calif.

COPYRIGHT 2006 Medquest Communications, LLC

COPYRIGHT 2006 Gale Group



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