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New diabetes drug

In March 2005 the FDA approved Symlin (pramlintide acetate), an injectable medicine to direction blood sugar for adults with emblem 1 and type 2 diabetes. Symlin is the single therapy for treating type 1 diabetes other than insulin. clan with type 2 diabetes already have several other emblems of oral therapies available.

Symlin is to be used solitary in combination with insulin to help lower vital fluid sugar during the three hours after meals. It is meant for patients who cannot achieve adequate vital current sugar control on intensive insulin therapy alone. So-called "tight" superintendence of blood sugar is desirable in all patients with diabetes to bring the risk of blindness, kidney disease, vascular disease, and other long-term moot points that diabetes can cause.

The safety and effectiveness of Symlin were studied in about 5000 tribe Side effects include nausea, vomiting, abdominal pain, headache, fatigue, and dizziness. Because of three areas of pertain to there will be a medication guide and a risk minimization action plan for the use of Symlin. First, the principal risk is hypoglycemia, an abnormally depressed concentration of sugar in the life-blood This risk is greatest in tribe with type i diabetes and clan with slow stomach emptying (gastroparesis), a long-term complication of diabetes. next to the first there is a potential for medication errors, specifically, mixing Symlin with insulin in the same syringe, which can alter the activity of the insulin. Finally, the potential for off-label use in family where the benefit-risk profile has not been characterized or demonstrated is also of relate to and will be monitored by the agency of the sponsor.



Symlin has not been evaluated in children. The therapy should not be used if race cannot tell when their vital fluid sugar is low, have gastroparesis, or are allergic to pramlintide acetate, metacresol, D-mannitol, acetic acid, or sodium acetate.

Symlin is manufactured by dint of Amylin Pharmaceuticals Inc. of San Diego.

COPYRIGHT 2005 U rule Printing Office

COPYRIGHT 2006 Gale Group



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