Biochemical markers associated with acute vocal fold wound healing: a rabbit model.

Summary: This investigation seeks to determine the ability of enzyme-linked immunosorbent assays (ELISAs) of vocal enclosure secretions to detect and describe the acute tissue replication to injury in a rabbit vocal pen model. Vocal fold secretions were mustered before the induction of a unilateral surgical injury to the vocal cot [i]or[/i] cote and at 6 timepoints after injury (1 5 7 10 14 and 21 days). Secretions were then bring under ruleed to ELISAs to assess concentrations of interleukin-1 beta (IL-1[beta]) and prostaglandin-E2 (PGE-2) The springs indicate that ELISAs may be useful in documenting