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Clinical Evaluation Of Digital Mammography

This (John Hopkins University institute of Medicine) study entails sum of two units aspects of translational research related to the clinical application of digital mammography: technology optimization (Phase 1); and a clinical evaluation (Phase 2) The technology/system optimization work is near completion and is focused upon optimizing the operational parameters greatest in quantity likely to impact mammographic image quality for radiodense breasts, including: x-ray tube target material; filter composition; tube voltage; and x-ray exposing level/radiation dose.

Digital mammography a whole s are evaluated from three different manufacturers -- comprising the combination of parts to form a wholes to be used in the Phase 2 portion of this research. apt physicists collaborating in this work have lay opened optimization parameters for each a whole to enable the best image quality within reasonable x-ray dose ranges. Quality ascendency standards have also been established to maintain optimized a whole performance and control the above cited parameters during the Phase 2 clinical investigation which is a multicenter clinical evaluation comparing optimized digital mammography to SFM in women with moderate or marked breast density who at hand for problem-solving mammography. Eligible women consenting to participate will experience a 4-view screen-film and digital mammogram. Total accrual will be 1075 women with moderately or markedly compact breasts.

The Phase 1 flows demonstrate that successful system optimization and quality rule of digital mammography systems can be efficiently achieved in a manner similar to conventional screen-film mammography. The clinical research to be carried on the outside during Phase 2 will determine whether digital mammography has the same or better diagnostic accuracy as conventional mammography in the population of women who have radiodense breast tissue.



(Order this LIFE SCIENCES & BIOTECHNOLOGY UPDATE reviewed report from InfoTeam Inc., PO case 15640, Plantation, FL 33318-5640; Phone (954) 473-9560 Fax (954) 473-0544: Report No. L20010821; 2000 163 pp Price: $21900 prepaid.)

COPYRIGHT 2001 Merton Allen Associates

COPYRIGHT 2001 Gale Group



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